I have a friend who uses the Bow Tucks bag that I gave her to carry her teaching supplies and items back and forth. However, in the past I have used heavy outdoor fabrics for tote bags, which are really sturdy. I would find a great fabric for the outside, making large pockets on either side deep enough for papers and folders. Inside I would use pockets all around the inside of the bag, and possibly adding a zippered pocket for items you don't want to lose. I would probably add a key ring, loop or something similar with a clip to hold your keys, which invariably go to the bottom of the bag. I would also add a sturdy insert in the bottom of the bag for extra strength. I've used plastic canvas covered with cotton batting, then covered with matching fabric to the bag, and some people use the plastic cutting boards you can get at the dollar store. I'm sure she's going to love whatever you do and you have lots of ideas here on the QB to help make decisions for what your bag will be.