I have done it, to make a quilt for my mother. She wanted a quilt the wrose way, but she lives in Puerto Rico. She didn't need it for warmth, ut for decoration. Making it with the top and the back alone showed the seams on the back, so I added a very old well washed sheet in the middle. white, so the color wouldn't show and old so it wouldn't shrink. It worked out great. She always have it on her bed and uses it to cover herself when the temperatures in the winter reach those harsh winter levels of 70 degrees at night. Don't I wish those temps right now.
Maria