No, but I do soak 100% cotton batting in the washer and line dry the batting. I honestly think it would almost certainly be fine to not pre-soak it, but I am really picky about getting rid of potential allergens.
I definitely would not actually wash it. It distorts the batting too much & leaves it really wrinkly. I try not to apply too much heat to the batting. Just a tiny bit to get the fold marks out if I don't soak it first (e.g., with wool batting).
The reason you don't need to pre-shrink the batting by washing it is because that 2% or so that it shrinks actually helps give the quilt that nice crinkly look.