For my mom's 80th birthday quilt, I made the front out of floral fabrics and the back was mostly all cat fabrics with a strip of fabric, different pieces sewn together, from the front. Plus one or 2 of the cat fabrics had both flowers and cats on them. I rarely, okay never, coordinate the 2 sides together. I like an unexpected twist on the back - even on wall hangings. I do make bindings that play well with both sides but I use a dark binding on quilts - like a picture frame.