I used Quilters Dream cotton batting for my grandson's T-shirt quilt, flannel backing and some flannel around the blocks. The shirts were fused with feather weight, 911. It was not too heavy at all. I quilted it on my Pfaff sewing machine. This was a good sized quilt. I did say at the time it was kind of like wrestling a bear to get it quilted, but I did it!
You should be fine with the plan you have and lucky you, you won't have to wrestle with it
I did get some of my ideas for his quilt by looking at a similar one at the LQS. It was on their long arm at the time. I think flannel and cotton batting is common for these cold Nebraska winters!