I have it in my spine and I have to pace myself when using the rotary cutter. I sew everything I can by can because I can sit and relax in my big chair when sewing. When I sew the binding on the with the machine I usually have to take a pain pill and lie down. I have some in my right hand but so far I can still hand sew. I started quilting because I had to find something I could do that didn't require me to stand or walk. I use to walk outside for exercise but not any more. If I hand't developed arthritis in my spine I am not sure I would have found this wonderful hobby quilting.