Yes, they are both basically the same machine. Feet and hoops are interchangeable. The Dream Machine has Disney designs and you can purchase Disney designs from the Brother website. The Destiny has designs from Nancy Zeiman, it you are unable to use Disney designs if that is what you like. I am not a fan of Disney and would not use that as a marker to purchase a machine. I have the Destiny and love the machine. Baby Lock has "the Love of Baby Lock" a 4 year membership to their online training videos. I got this and have found the videos to be very helpful.
Either machine are wonderful machines and very user friendly.