I will set up my quilting frames (as long as I don't have a quilt on them), and lay out the quilt that way. If I do have a quilt on the frames, then I will do it on the floor, if I am going to machine quilt. If I am going to hand quilt it, then I put it on a shelf until I am able to get it going. I prefer to use the quilting frames if I can, just because it is a whole lot easier.