I know I am in a minority, a very small minority, but I avoid chemicals whenever possible, basically for health and environmental issues. I prewash all fabrics to remove chemicals and don't add any back if I can help it. I avoid products with ingredients I can't pronounce. There are exceptions like fusible for applique because I don't have another alternative. I even use natural cleaners in the house when I can. Chemicals are so pervasive in our lives that I use more than I realize or want to. But if a chemical or product causes a health issue, it isn't worth it. I used Magic sizing on the second quilt I ever made, but I had breathing issues so never again and my quilts have turned out fine.