If your set up and not going anywhere it would be fine. But if your traveling no! The bounce back there is pretty hard and does a bit of damage to more sensitive items not heavily strapped in or packed. You would need to take your machine off and wrap it up and probably store it up front in the front bedroom that is the softest ride as it is over the truck axel That is where I store anything electronic or sensative when we go down the road in ours. Things can really get damaged in the back if sensitive to vibration.
So you would need to decide how to handle it and how often you would be moving and traveling. You would need to relevel after every move as you seldom end up set on a perfectly level spot. Then unpack your machine and remount it. You would not be able to just leave it set up while you move and would have to really secure the frame to the tie downs so it would not move around either.