I swear by Comfort Thimble. While I don't have large fingers the thimble does come in L and XL. I don't know anything about the vendor for the this link but see that they offer all sizes and at the best price I have seen too.
http://www.quiltershaven.net/SearchR...himble&Submit=
The thimbles are so comfortable and I have not had any needles poke through and a low rate of needle breakage with using one. I bought one at a quilt shop while on vacation and have ordered more since as back-up.