I am curious about when the glue doesn't come out of the bottle easily. Granted, I don't have carpal tunnel, shoulder, wrist, thumb, etc. issues (at least not yet!) but when I turn the bottle over, gravity takes care of much of it and it drizzles out in a thin bead. It doesn't take much pressure at all to get it going. If it gets down to the end of the bottle I give it a shake or two and then things start flowing again.