I make a test block, then usually cut the entire quilt to get that over with. I am very meticulous about labeling each block if they are different, in ZipLock baggies, or pieces if they are all the same. As I finish a block I pin a small Post-it always on the top left corner, signifying which block (I do a lot of applique), then assemble by rows on my design wall. I always cut the borders a wee bit long and measure to size once the top is completed and ironed.