How big do you want to make it? I made a throw for my niece's family in WA using Mariner's fabric on one side and the Seahawks on the other. The fabric is 59 inches wide, so used 2 yards then just quilted the fabric together with batting in the middle, and sewed on a binding. For my daughter I collected all the MLB teams and cut out hexagons and put them into the "I Spy" style with the SD Padres on the other side. For her NFL quilt I collected the all the teams, then cut them into 6.5 inch squares, put them into the their appropriate divisions, used red and blue to frame the division - depending on which division they are in (ACF is Red and NFC is blue) then used the SD Charger fabric for the back of the quilt.
They are all very basic quilts. My DD's friend is an Oakland Raider fan, so I used 2 different Raider fabrics for a quilt for his 30th birthday.
They are not very imaginative but well loved, so for me that is all that matters.