I have sewn for years but quilted for only a few years. I try to go through my fabric and purge what I don't want every so often just like I do my books and other belongings. There are churches in the area that sew quilts, and a group that sews bags for people ending up at places like Ronald McDonald houses while their loved ones are in a medical emergency. I've read on this board of many other worthy groups that make donation quilts and items. Why keep what you have no interest in using when others can use it?
Having said this, I do feel like I need to be more careful when I am turned loose in a fabric store......