I use sticky notes. If they don't stick I pin them. I do one horizontal row at a time and press. Then when I sew the rows together, I do 2 and press, then sew 2 together and press. I recently did a queen sized quilt that was 14 x 14 blocks, and this method worked fine and I didn't have a very big quilt to press until the end. Made it much easier.
Sue