Do you have an extra machine to leave set up in the extra bedroom? If so, I see no reason why a second sewing area would not work. You could use your basement area to cut out your projects on the weekend and then just have a machine and perhaps a small table with a small cutting mat and ironing pad on it. What else would be in the room, a bed, dresser? I do most of my sewing in a bedroom and use the bed as my "horizontal design wall". Let us know what you come up with