I found that I had to experiment to find what worked the best for me. Realistically, I don't have the space to keep a long queen size frame set up all the time. Watching ergonomics is important so I can prevent back, shoulder, and neck pain. I experimented with a few lap frames and then with hoopless methods. Found out I liked to quilt a thread-basted quilt sitting in a firm ergonomic office chair without a hoop, but with a table or my bed supporting the weight of the quilt.
I also tried out many kinds of thimbles, needles, and stitching styles to find a comfortable method that would not only yield consistent stitches, but minimize hand pain. I watched lots of YouTube videos for tips.