I don't have the 6600 but do have the Janome 423S. It is my first machine and I picked it out about 2 years ago. I have been making all my quilts on it ever since. I taught myself, thorough hours of practice to do FMQ and I do FMQ on this machine and did thread painiting using this machine on the Christmas Quilt I made this year. So if I can do it on the less expensive model Janome I see no reason why you can't do it on your 6600 Janome.