I just always expect a red fabric to bleed. I made a red and white quilt for my mom and was so disappointed after finishing it and I hadn't prewashed a black and one of the reds. As far as I'm concerned, this is the best and final answer for bleeding of commercial fabrics:
http://www.colorwaysbyvicki.com/save...ing-quilt.html I used this several years after making the quilt and it worked!!!!