Do not treat the quilt top with Retayne. It will set any bleeds. Honestly, I wouldn't worry about it (but I would stop using water spray when ironing to prevent more bleeds). Just use Synthrapol in the first wash along with a LOT of water. Synthrapol suspends unset dye particles in the water so they do not settle in other fabrics. Synthrapol will lift out the existing bleeds too.