Wow RedGarnett what a great comment! It is so true too! We do need to know how the OP quilts too, as she did not say. by hand, domestic machine or longarm. There are so many possibilities! I actually think this quilt would be really cute done in big stitch hand quilting with a very heavy perle cotton like an 8 wt. Done in different bright colors to match all the calico prints. I would do a simple 1/2" or 1" echo on the inside of every square. In the white squares I would do the colored thread sprinkling the bright colors about. On the prints I would use white perle to contrast so it would show.