First, make up your mind if this is going to be a keepsake/wallhanging or if this will be a drag around and cuddle quilt. I would probably quilt around the pics and then follow the batting instructions as to how far apart the quilting needs to be on the sashings for a keepsake. For a cuddle quilt I would put as little work in to it as possible but so it will hold together. Maybe quilt around the pictures and tie in the sashings with just a little quilting there. I am concerned that photos will not be very permenant with a lot of washing so just give it in love and be happy with the love it gets. When it wears out it wears out. Hope this helps.