I think one of the most important things to be considered is not rushing. From conversations over the years I think most quilters find the basting the worst, most difficult and unsatisfying part of quilting. If the object is to quilt the quilt, then embracing basting as part of the whole is really important and to do it well means to not rush the process. Practicing on smaller quilts first before doing a huge quilt might make the task a bit easier because it is a learned thing to do. Learning every process and step along the journey is important and equal to the enjoyment and satisfaction at the end.
Over the years I have learned to work slowly, don't rush to "get it done". Enjoy what you are doing every step and stitch along the way.
peace