Originally Posted by Bree123

I pre-wash everything that comes into my house due to contact allergies. Doesn't matter if it's a 2.5" mini charm. I use the soak cycle with cold water (Tap water cold if that's available) and a small amount of detergent. When they're done, I dry them partway on Low Heat in the dryer & iron them the rest of the way dry (or lay flat to dry if it's too late at night when I pull them out of the dryer).

Quality fabric really doesn't shrink or fray that much anymore. If you want to be overly cautious, you can run a zig-zag or overcast stitch along the edges of the pre-cut. I've done that once or twice back when I bought cheapy fabric & it works fine. The other thing I've done if I'm going to be cutting it down further (e.g., for applique) to where I have more than 1/4" extra from the edge is to run a narrow bead of Fray Block or Fray Check along the edge. I wouldn't recommend leaving that on there, but if you have as little as an extra 1/8" (meaning 3/8" total), you can easily trim it off.

Note: if you suspect the end-user is going to be washing the quilt in warm water or a medium dryer, you will need to pre-wash in those same conditions -- and then I would definitely recommend securing the edges with stitching because heat & and agitation will both cause the flannel to shrink and fray more. There's no need to wash in those conditions if the recipient is willing to wash on gentle cycle, cold water, low heat tumble dry, but flannel that was pre-shrunk under those conditions will shrink again if exposed to higher heat and/or more agitation in either washer or dryer.