There are many different ways. For your first try, I would go very simple. Both Missouri Star Quilt CO and Quilt In A Day have videos that are easy to follow. Eleanor Burns (QIAD) has many and would probably be the best for your first time. She uses the fusible on the back, presses it and then blanket stitches the edges. This would let you see how you would change it and slowly morph into a completely hand done one. Then see what you like and don't like. I might try these on either a scrap or perhaps a pillow or tote bag front rather than directly on a quilt top. Just, keep in mind, the way you find the best is the right way!