Does your machine have either the Pfaff IDT or a walking foot?
Could you make a "sample" to practice with? I am wondering if you could do some reverse stitching here and there to get from point A to point B instead of turning the whole piece completely around?
I "discovered" that when I was trying to sew on some 1/2 inch squares of velcro - then I would only have to make a 1/4 turn and that was less painful than trying to make a 1/2 turn.
You could also make a drawing (or take a picture) of your project and draw lines on that to plan ahead your "route" while quilting it - if you could tolerate crossings or occasional overlaps, that might also make it easier?