so are you going clear across IA on I-80 or might you be dropping south on, say I-29 from Omaha/Council Bluffs and then across hwy 33 (or maybe it's 36) to Hamilton, MO, home of all 13(and counting??) Missouri Star Quilt Shops?? Then from there a quick jaunt down I-35 to I-70 and straight into St. Louis! (or maybe this could be the way home!)
If sticking to I-80, lots of shops in Des Moines area and there's the Amana Colonies and Kaloma, IA (just off the interestate) has quilt blocks on the street sidewalks!