Is this wool tweed? How will it behave if it's washed? Tweed is a loose weave, so you would want to use a larger seam allowance to avoid fraying. I think I would take a few pieces, make a very small sample quilt (maybe 18" square) using quilting cotton for the backing, use some batting if you have some on hand, quilt it and finish the edges, then wash it and see if you like the result.