I use the second largest bedroom for my sewing room. I have a double closet and my husband built shelves in it- holds a ton.
At first I didn't like being away from the kitchen, laundry etc, but now i prefer it that way. And all my stuff is in one room so there are no messes anywhere else.
My only companion is my cat, Carmello
But if things get too messy he gets mad at me!