I make quilts that go to people that may or may not know "the correct way to wash a quilt."
Therefore, I try to have fabrics that can just be "thrown" in the washer with ordinary detergent and be treated like "ordinary" laundry.
Of course, I would prefer that the people use care (and good sense) when they wash their quilt - but when one has a baby that is throwing up or suffering from diarrhea - "proper laundry methods" probably are not the most important thing on the caretaker's list. Just get the thing washed and the icky stuff off it!
The only things I really worry about - as far as the quilts I've sent on their way - are bleach, burns, and rips.
Even with washed fabrics - letting a wet quilt "set" in a was is asking for trouble!