I think about this question, too. My sisters and mom just say "bring them on" because they love them and are sentimental. I make pillows to match different rooms in house or quilts I've made them. Maybe doing something that coordinates with nieces quilts would be fun to do. The nieces may "burn out" on quilt making so I imagine there will be lots of opportunities to do a quilt in the little one's lifetime. I love the ideas on this thread