It is well worth the time to (window) just leave the perimeter and cut away the centre, if the shape is large enough. It leaves the applique feeling much softer. I usually get all motivated picking my fabrics when I start a project and forget to cut them out though. It's not a disaster with the steam a seam 2 light, it is quite soft (haven't tried misty fuse). But wonder under was stiff as a board and very noticeable on the finished quilt.