Not quite as far south as you indicated, but have you been to Rainbow's End in Dunedin? (
http://www.rainbowsendquiltshoppe.com/about) Wonderful selection! Parking can be a bit of an issue, but they allow you to park behind their cars (on the back side of the shop) or the owner of the restaurant across the street (Lobster somthing) allows parking during slower times. Don't think about parking in the spaces at the little store across the street, possibly a blinds shop - owner will run out and yell at you.
I don't care for Cotton Patch in the University Park section of Sarasota. It used to be on 41 S (Tamiami Trail), but they moved and it's never been the same.
Will follow thread as we have a condo on AMI and now that I am retired, I finally get to go down at least once a year.