You are already neat and tidy and organized, so I'm sure your sewing space is seldom out of control, if ever. To me, the space with the best natural lighting is the best space for everything except sleeping. My sewing room is in the bigger of the two spare rooms (emptied when older children flew the coop) and I chose it because it's much brighter and bigger than the north-facing bedroom. Even though I like guests to sleep in that room because it has a queen bed, I do have to straighten it up (quite a bit!) . Thankfully, I always get a lot of advanced notice.
I like visiting people in their hobby areas. Certainly is a conversation starter and I learn from people things I didn't know before if they talk about their hobby. Figure out what arrangement will make you feel satisfied and productive and then go for it.