Yes, I made a DP9 for my brother about 10 yrs ago (?) because I wanted something fast that still looked like it took some time to put together. I used 6" or 6.5" and 9 different fabrics - looked great and it did not matter that they were bigger blocks. As far as a bargello - not sure - but if you keep your subcuts in line with the larger strips (that means not cutting into skinny strips less than 1.5") then it should be fine. Or you could cut those 6/5" strips into 3" & 3.5".