I know you do a lot of fusible applique so you may want to ask them if they have any issues with it. Some do, some don't. Also I have seen a lot of amazing quilting done on DSM using walking foot and straight line quilting and there is no reason you can't do both hand and machine on any quilt. I used to do that a lot in my hand quilting days. I would hand quilt the fussy motifs that I knew I did not have the skill set to do on my DSM and then do straight line echo quilting with my machine. Like this one:
Paw of the Bear
So that is another option for you to consider.