I'm a two time survivor and I've never had any problems with the port and chemo. I wore button front shirts, V-necks, and scoop neck or boat top neck. No need for a zipper top, in fact I wouldn't advise it. After several rounds of chemo things change, skin gets dry and itchy. I would not want the zippers on my skin. Chemo is tiring, if she has a t-shirt on she can go home and crash without changing her top.