As someone who has run a small business (non retail) for better than 30 years, my best advice is to ease into it slowly. As has been mentioned, the monetary outlay to open a store is considerable. I would start by selling online even if you have to lease a storage area for your inventory. Work with the public for a while and see how you like it. Not everyone you deal with will be nice or even civil. Don't quit your day job until you are making enough money to be able to support yourself. A small retail establishment can not turn a profit for a year after opening. Bank all the money you make while you are still working at your regular job to reinvest in your inventory.
We started our business out of necessity (no jobs in the area, but my husband had a really good reputation in his field and could get some work). It was a hard road and not just for the first few years. It was rough for the first 10 years. Very up and down and not much security or stability and a whole lot of work. In the end, it has turned out to be a great deal for us, but it's definitely not for everyone. There's a lot of stress and a lot of work and when you are in it alone, it will be even harder.