I have an adblocker on both Edge and Chrome (AdBlock Plus) - so far the latest update from MS hasn't caused issues.
My issue is with the pages that ask to have the blocker disabled because they need the revenue from the ads to be able to provide content free. If the dratted ads didn't slow everything down so much or cover everything up, I would happily allow ads. So someone is shooting themselves in the foot! Most information is available somewhere for free.