For edge to edge or border to border, I rarely mark. I'll mark registration marks (chalk) on the border so I can get designs spaced consistently. Same with marking the middle of a block that I will be going into and want consistency. I use a lot of rulers so I don't mark actual design lines as much, but I do lots of practice sketches beforehand. When I'm doing lots of negative space where I'm quilting a modern design, I will mark (either chalk or water soluble blue or air soluble purple) some motifs or use a stencil; and then mark some "pathways" (a'la Krista Withers). I get lazy and think I should do more marking actually! I have used press n' seal and laid out a whole design--but that's rare.