How do you plan to do the quilting? I quilt on a longarm, and I always wash my fabrics. I take them out of the dryer before they get very wrinkled, and then I stretch the backing on the frame. If there are wrinkles, a spritz of water and a tightening of the frame get them out quickly. If you're using a longarm, you can try this method. If you're sending the quilt to a longarmer, check with her to see if she's willing to do this. It does take a little more time to let the backing dry before advancing it and spritzing again.