You are wise to do your own research and planning. It really does depend on your individual needs and how you like to do your sewing/quilting tasks.
Do you have drawings or pictures to post? That may help with more suggestions for your room.
I don't have a LA but can tell you when you get it right there is a feeling. I moved some tables and machines in my sewing room. Then had to move them back to original layout since it just wasn't right.