For me I would get the ink out first. I would try water first on a Q tip to see if it is water solvable. Next I would try hairspray on a Q tip to see if it is ink. If the ink came out with either of those, I would gently hand agitate it in the bath tub, drain away the water, agitate it again to rinse, drain and carefully lift it out and dry it out flat on a safe surface.
I would not want to put in the work applauding or quilting to find out the ink won’t come out. If the ink is permanent and well done, I might hand embroider over it. Good luck!