I found that malic acid is amazing. It is the acid found in apples. You can get it at GNC or Vitamin World for about $8 a bottle. One tablet morning and night. There are no adverse effects, no problem mixing it with other meds AND you will know within 24 hours if it will work for you! It is the difference between getting out if bed or not for me. Hope it helps some of you. Blessings to all.