We might have overnight or longer-stay guests once or twice a year. My sewing room has a queen bed, which is where I sleep all the time. (We both snore and I go to bed much later than hubby, so it works for us,) If we host a couple, they get the room. If a single, I have recently redecorated a spare bedroom with a twin bed.
Here's my sewing/guest room when it's company ready (a rare sight).
My Sewing-Guest-Happy Place