I purchased the same set up as yours, the megaquilter on the same frame. After some practice on it, it started to skip stiches, with mine it was the stitch regulator sensor wheels. While moving your machine, watch your sensor wheels if you have a stitch regulator on your set up, if you see them pause (or skip) you'll have skipped stiches. I cleaned and oiled the ones on my set up and it solved the issue. Good luck. Hope you get it figured out.