When I do panel quilts for babies and small kids, I like to hand stitch in the panel and then meander the rest, but not too much. Hand quilting is softer, not stiff and adds a really personal touch to the quilt. I usually write the child's name with my meandering stitching and tell the recipient to find their name in the quilt. They are so proud of their name being "hidden" within their quilt. Have fun with it.