I found a stack of about 700 unused 2.5" Y2K squares recently and started looking around, I think I could pretty much quilt for the rest of my life using nothing but 2.5" cuts. It's no wonder that my 2.5" ruler is one of my most often used.
Keep in mind that you can take two squares and sew along the diagonal, cutting the excess off of one half and you would end up with a 2.5" HST so you aren't limited to squares alone.
I decided to do a traditional Flying Square block, super scrappy but they are not all unique. I avoided partial seam blocks for a long time but one reason I chose to do this is my new-to-me sewing machine (instead of my old vintage machine) has a thread cutter and I'm trying to learn how make use of the machine. Partial seams aren't really that big a deal but I was much less covered with threads afterwards.