If it is substantially off, I adjust the seam width a tad or two, but if it's a little off, I let it go. None of my quilts have ever gone to shows or have hung on walls. I figure if the defect won't be spotted by someone riding a horse at a gallop near it, it's just fine. My quilts are baby and kids quilts made to be used, enjoyed, slept under, wadded up, crawled upon, ... and lots of etc. And, when the baby out grows it, the puppy or kitty can enjoy it, too.